Early symptoms of SLE might be vague, nonspecific, and easily confused with other pathological and functional disorders.

Symptoms may be transient or prolonged, and individual symptoms often appear independently of the others.

Moreover, a patient may have severe symptoms with few abnormal laboratory test results, and vice versa.

The below lists the range of clinical symptoms seen in patients with lupus over the lifetime of the disease.

Symtoms of SLE Fatigue Arthralgia Arthritis Fever (>100 °F) Skin rashes Anemia Edema Pleurisy Facial rash Photosensitivity Alopecia (hair loss) Raynaud's phenomenon Seizures Mouth or nose ulcers

Source: National Institutes of Health, U.S.Dept of Health and Human Services