1 IN THE CIRCUIT COURT OF THE STATE OF OREGON 2 FOR THE COUNTY OF JACKSON 3 4 In the Matter of the Marriage of: ) ) 5 SUSAN SAMORA COUTSOUKIS, ) ) 6 Petitioner, ) ) 7 and ) Case No. 94-3846-D-3 ) 8 PHOTIUS COUTSOUKIS, ) ) 9 Respondent. ) __________________________________) 10 11 12 13 PERPETUATION TESTIMONY OF 14 HELEN SKOUTELI, M.D. 15 16 BE IT REMEMBERED That the perpetuation testimony 17 of HELEN SKOUTELI, M.D. was taken as a witness on behalf of 18 the Respondent before Debra J. Dugan, a Certified Shorthand 19 Reporter for Oregon, on December 4, 1996 beginning at the 20 hour of 9:35 a.m. at the office of Patricia Crain, 800 W. 21 8th Street, Medford, Oregon. 22 23 24 25 2 1 A P P E A R A N C E S 2 3 FOR THE PETITIONER: PATRICIA CRAIN Attorney at Law 4 800 W. 8th Street Medford, OR 97501 5 6 7 FOR THE RESPONDENT: CRISTINA SANZ Attorney at Law 8 900 W. 8th Street Medford, OR 97501 9 10 11 12 13 14 15 C O N T E N T S 16 Examination by: Page: 17 MS. CRAIN 4 18 MS. SANZ 20 19 20 21 22 23 24 25 3 1 S T I P U L A T I O N 2 At said time and place the following stipulation was 3 entered into between the attorneys present in behalf of the 4 respective parties: 5 IT IS HEREBY STIPULATED that all irregularities as to 6 notice of time and place and manner of taking said 7 perpetuation testimony are hereby waived. Parties have 8 stipulated to perpetuate testimony pursuant to ORCP Rule 9 39(i), and waive notice and objections to notice. 10 IT IS HEREBY STIPULATED that pursuant to Rule 11 39(i)(6), the perpetuation examination shall proceed as set 12 forth in subsection D. All objections to any testimony or 13 evidence shall be made at the time of the deposition and 14 any objections not made at the deposition shall be deemed 15 waived. 16 IT IS HEREBY STIPULATED that the reading and signing 17 of said perpetuation testimony by the party and the filing 18 thereof are hereby expressly waived. 19 ---oOo--- 20 21 22 23 24 25 4 1 HELEN SKOUTELI, M.D. 2 was thereupon called as a witness on behalf of the 3 Respondent and, after having been first duly sworn, was 4 examined and testified as follows: 5 6 EXAMINATION 7 BY MS. CRAIN: 8 Q Could you please tell us your full name? 9 A My full name is Helen, with an H, Skouteli, 10 S-k-o-u-t-e-l-i. 11 Q And of what town are you a resident? 12 A Athens, Greece. 13 Q Could you tell me just briefly your medical 14 qualifications? 15 A I'm a medical doctor of the University of Athens. 16 I'm a fully licensed pediatrician in Greece. 17 Q You also practiced or studied in the United 18 States? 19 A I was a research fellow at Childrens Hospital in 20 Boston and a research fellow in epileptology also in 21 Boston; three years, not in a row, in various, you know, 22 different times. 23 COURT REPORTER: Could you say that research 24 name again, please? 25 THE WITNESS: Research fellow is a 5 1 fellowship, but, you know, people who are research 2 fellows, they do not practice clinical medicine; 3 they're involved in research studies. 4 BY MS. CRAIN: (Continuing) 5 Q The court reporter did not understand the word 6 that you said for the research that you were in, the nature 7 of the research? 8 A Well, I was a research fellow in pediatric 9 neurology, which is my field now; and a research fellow in 10 epileptology, EEG, electroencephalogram. I also spent two 11 and a half years as a registrar in London in pediatric 12 neurology at Hammersmith Hospital; that was prior to my 13 coming over to Boston. 14 Q What was the name of the hospital there again? 15 A Hammersmith; for post graduate medical school. 16 Q Thank you. The court reporter is attempting to 17 type down everything you say, so we want to make sure we 18 get the spelling correctly and the pronunciation, so that's 19 why we keep interrupting. 20 A Sure, no problem. Hammersmith is 21 H-a-m-m-e-r-s-m-i-t-h. 22 Q How long have you now been practicing in Athens? 23 A Since 1989. 24 Q In the course of your practicing as a doctor, did 25 you come in contact with Theodora Coutsoukis? 6 1 A Oh, yes, yes, twice. 2 Q Can you tell us the nature of your first contact 3 with her? 4 A Our first contact was when the family was 5 visiting Greece in, what was the year, if you could help, 6 in 1990, I think, when she was six months old. When was 7 she born? 8 Q Hold on a second, I have to look. 9 MS. SANZ: I think it's 1994. 10 BY MS. CRAIN: (Continuing) 11 Q 1994 perhaps? 12 A Yes. Well, the first summer of her life, put it 13 this way. 14 Q That's fine. 15 A The first summer of her life, the family was 16 visiting relatives in Greece, because Mr. Coutsoukis is of 17 Greek dissent, has family here in Athens. So when they 18 came, they saw a lot of pediatricians who saw Teddy -- 19 Theodora -- and she was, I believe, either six or nine 20 months old. And he was a little, you know, concerned about 21 her neurological development; not the pediatric 22 development, the physical characteristics, but the 23 abilities and the milestones. 24 So this pediatrician referred her to me and they 25 all came to my office: Mommy, daddy, Theodora, and 7 1 Theodora's aunt, Mr. Coutsoukis sister, I believe. That 2 was my first contact with the child and her family. 3 Q And tell us what you observed? 4 A From the medical point of view, or from the 5 social point of view? 6 Q Both. 7 A Both? 8 Q Yes, please. 9 A Okay. Well, from the social point of view, nice, 10 kind people, you know, English speaking, they preferred to 11 speak in English so that mommy can understand as well. You 12 know, no social problem, I mean obvious to me or anything. 13 From the medical point of view, the child was, had 14 psychomotor delay. She was behind in all areas of 15 development: Motor, and interactions, social interaction, 16 mental areas. 17 Q What did you do? 18 A Well, I told them that I think that she's behind 19 a few months. I didn't, you know, aggravate things a lot 20 because apparently I was the first one to announce the 21 news. And, you know, it's difficult sometimes. 22 Q For parents? 23 A Yeah, very hard from the first appointment. And 24 I said, you know, I see a developmental, a mild 25 developmental delay and I think you need to do a basic 8 1 workup to discover the etiology of this. So, you know, I 2 proposed a list of blood tests and workup in general. And 3 they decided to have this workup done in the United States; 4 and of course I agreed, I said, you know, if you're going 5 to go back, you better have it there, I mean it's much 6 better. 7 Q Was that the end of the first contact you had, 8 then? 9 A Yes. Yes, I don't remember saying anything more. 10 I mean, it was an hour's appointment, of course we said 11 more; but it was more towards the, you know, the outcome, 12 is she going to recover from that, what do you think this 13 and that. Of course I could not answer all these questions 14 because the outcome is related to etiology sometimes, and I 15 was not clear as to what the etiology was for this 16 disorder. 17 Q After the family returned, then, to the United 18 States, did you continue in contact with them and with 19 doctors here? 20 A Yes. In fact, they had the workup done in the 21 United States, and Mr. Coutsoukis sent me the letters of 22 the doctors. And they had some examinations done and they 23 were not conclusive to the etiology of the disease again. 24 Q Was there a general consensus on what the 25 etiology might have been? 9 1 A No. But the general consensus was that indeed 2 the child was a few months behind. 3 Q Okay. 4 A So everybody agreed; it was not my only, my 5 opinion only, you know, here in Greece. But even the 6 doctors in the States agreed that she was developmentally 7 behind. But we could not find etiology of the organic 8 causes, where most of the organic causes, I would say all 9 of them now, they were excluded by blood tests and CAT 10 scans and all this, you know. 11 Q Okay. Did she, to the best of your knowledge, 12 begin any physical therapy, or occupational therapy? 13 A Yes. She had physical and occupational therapy; 14 and I had, on a couple of occasions, the opportunity to 15 review tapes, video tapes of her progress. They sent me 16 video tapes in Greece, and I had the chance to review them 17 and make some observations or suggestions. 18 Q Did you continue to do -- 19 A Not a real medical follow-up, as you know; we are 20 quite a distance from the United States. But I had some 21 correspondence with Mr. Coutsoukis, he wrote to me her 22 progress; and Mrs. Coutsoukis called me twice. 23 Q Did you also -- 24 A I'm not sure twice, maybe more than twice; but I 25 heard her voice over the phone a few times. 10 1 Q Did you also communicate with Diane Williams, 2 the -- 3 A Yes, the pediatrician in charge, yes, I sure did. 4 Because, you know, in the process of her developmental 5 delay, Teddy came up with some seizures, convulsions, fits, 6 epileptic seizures. 7 Q And that was later? 8 A That was later, that emerged later. It was not 9 there before; this is something that came up later in the 10 course of her disease. 11 Q Did you assist Dr. Williams in regards to 12 prescriptions and treatment? 13 A Yes. Yes, I did. In fact, I read the EEG's, I 14 gave some suggestions on the EEG's, they were sent to me, 15 mailed to me in Greece. And I suggested the use of the 16 medication that everybody would agree, it's an 17 internationally approved medication for the seizure 18 disorder, that particular one, called Depakine Sodium 19 Valproate. 20 Q Can you spell those? 21 A Yes. Depakine is the commercial name, Depakine 22 and Depakote are almost synonymous in the United States. 23 D-e-p-a-k-i-n-e, that's the commercial name. The substance 24 name is Sodium, sodium like potassium sodium. 25 Q Yes. 11 1 A Valproate. Valproate is spelled 2 V-a-l-p-r-o-a-t-e. 3 Q Is this a drug that's commonly available in the 4 United States? 5 A Yes, very commonly available and very common in 6 pediatric populations with this particular type of seizure 7 disorder. 8 Q How did the child do with the prescriptions? 9 A She did, she did well; I mean, she had some 10 follow-up blood tests because this drug, as any drug, has 11 some side effects, it's not without any side effects. Of 12 course all this was explained to the parents; not to bother 13 them, of course, because they were not present in front of 14 me at that stage. You realize that the child had seizures 15 in the States later on. So some of the side effects -- not 16 some, all the side effects were explained to them; and they 17 had blood tests to monitor for any of those side effects. 18 And, in fact, she did not have any harmful side effects. 19 But Depakine alone failed to improve her EEG. 20 The EEG is a brain wave test that we repeated a few times. 21 Q So what was done next? 22 A So we decided to prescribe as an add-on therapy, 23 a second medication which is called -- I don't need to give 24 you the Greek name, I'll give you the international 25 chemical name, it is called Clobazam, C-l-o-b-a-z-a-m, 12 1 Clobazam. This medication is an antiepileptic medication 2 again, and it's not marketed in the United States, but it's 3 fully licensed in England, Europe, Greece, Italy. 4 Q How did she do with that medication? 5 A According to Photius, she did well. According to 6 Susan, because I talked to her over the phone a couple of 7 weeks ago, she feels that it didn't help. 8 Q Okay. Have you seen the child a second time? 9 A Yes, I saw the child a second time last year when 10 I was visiting Boston, just, you know, as a visiting fellow 11 or something. The chance to see Teddy and her father, they 12 came over to Boston to see me; and of course it was a big 13 time lapse, the baby that I had seen in Greece the first 14 summer of her life and now she was a grown up girl and she 15 was walking independently. Her balance was very poor. She 16 had much better social response, she was responsive to me 17 and interactive; she was not withdrawn or anything, but 18 still with developmental problems, but I guess bridging the 19 gap slowly. 20 Q Did you observe her -- 21 A I -- sorry. I did not notice any side effects 22 from the antiepileptic medications. I could not judge 23 improvement because I was not there at the time that she 24 started having seizures, you see, to compare how she was 25 prior to the seizures and how she became afterwards, after 13 1 the control. Because clinically, she has no seizures 2 anymore. You don't see any seizures; you see only a normal 3 brain activity on the electroencephalogram. 4 Q Is there any consensus that this is epilepsy or 5 some other disease? 6 A I think, I think this is epilepsy. This is a 7 child with epilepsy, and this is related to her 8 developmental delay. They come all in the same diagnosis, 9 you know, the one that we don't have in hands right now. 10 Q This is something that you and Dr. Williams and 11 the other doctors would agree with? 12 A Well, Dr. Williams agrees, yes; and I guess the 13 other doctors would agree, too. Because Susan wants to 14 take her to New York to some big center; and I said yes, of 15 course, you know, it's nice to have the agreement of more 16 than two or three people, you know. 17 Q Okay. And when you were seeing her with her 18 father, that was approximately last Christmas of '95? 19 A Yes, exactly, exactly. 20 Q Okay. Did you observe the interaction between 21 father and daughter? 22 A Yeah, it was very good, very friendly. She felt 23 very secure with her dad. I mean, you know, they look 24 very, very friendly to each other. She would do things for 25 her father that would not do for the examiner. 14 1 Q During the time that you have been involved with 2 this family, has the father expressed appropriate concern 3 about the daughter? Could you hear my question? 4 (Short interruption.) 5 BY MS. CRAIN: (Continuing) 6 Q Dr. Skouteli? 7 A Yes, yes, yes. We got disconnected. I'm here. 8 Q I believe the last question I asked you was over 9 the time that you have been involved with this family, has 10 the father expressed appropriate concern and care for the 11 child? 12 A Oh, yes, yes; correspondence and phone calls 13 and -- oh, yes, yes, very much so. 14 Q And would you describe the relationship between 15 him and his daughter as a close relationship? 16 A That's what it seems, you know, when I saw them 17 in Boston; sure, very close. 18 Q And so the only time you have seen the mother is 19 the once in Greece, and then you have spoken to her on the 20 phone? 21 A We talked over the phone a few times. She was 22 kind enough when I was in Boston on some other trip, to 23 send me a present in my hotel, and called me. And she 24 called me a couple weeks ago here in Greece one night. She 25 was concerned that the second medication that we added had 15 1 no effects. And she said, you know, I think it's not doing 2 any good, and the new EEG is the same and the people from 3 here cannot find any difference; we'll send you the reports 4 and the actual EEG's and you have to decide what you want 5 to do with the second medication. 6 Q Okay. 7 A I talked to her over the phone, I mean, you know, 8 a few times; not as frequent as I talked to Mr. Coutsoukis. 9 And we did not write to each other. You know, with 10 Mrs. Coutsoukis, we had the medical correspondence between 11 the two of us. 12 Q Okay. 13 A But, yes, I talked to her. But I met her in 14 person only once, Mrs. Coutsoukis, this is true. 15 Q Did Mr. Coutsoukis also ask you for literature 16 on -- 17 A Yes. Yes. 18 Q -- his daughter's? 19 A Autistic features, seizures, you know, some 20 syndromes I had suggested because I had some suspicion that 21 she might have had a syndrome called happy puppet syndrome. 22 But this, I guess, was ruled out by the appropriate 23 genetics examination that we suggested. 24 Q Okay. 25 A So she does not have this syndrome. That was one 16 1 of my thoughts. 2 Q What would be your recommendation for how the 3 child should be cared for and treated? 4 A Treated with interventional therapy; I mean, from 5 the point of view of epilepsy, I'm sure that she needs some 6 medication. Now, I cannot really decide myself if the 7 second medication does good or no good because I'm not 8 close to her; I don't follow her up every couple of months 9 or three months or so, you know. But the first medication, 10 the Depakine, I think is necessary. So that's one point of 11 pharmaceutical intervention for the epilepsy is necessary. 12 The other intervention should be the physical, 13 occupational, you know, educational therapy for her 14 developmental delay. 15 Q Would she need that on a daily basis, in your 16 opinion? 17 A Well, you see, the ideal situation, it lists here 18 in Europe is to go to a special kindergarten where she 19 could have it all in the session in the morning. Yes, like 20 a couple of hours every morning; that would be the ideal 21 situation for my country and for Europe. 22 Q And as far as the rest of the day, say, what 23 should be done with her by her parents, for example, what 24 would you recommend? 25 A Well, I mean, they, I guess they should try and 17 1 be available to her. And I know that this is difficult, 2 since they are both working, I understand. But the more 3 available they are, I guess the better, because she needs 4 them. 5 Q You told me -- 6 A But the specialized person can also take care of 7 her at home, I guess, right? I mean, it's not that only 8 her parents can do things for her. 9 Q Sure. Do you feel that maintaining the 10 relationship that she has with her father would be of 11 importance? 12 A I see her very attached to him, you know. I 13 think any child that you would try to disconnect her 14 completely or incompletely to somebody who is attached, it 15 hurts. 16 Q Okay. Would that affect her ability to develop? 17 A Not, not her organic ability, but her 18 psychological ability, yes, I think so. 19 Q Do you -- 20 A It may -- maybe she's attached to her mother the 21 same way, but I didn't see it because I did not have a 22 chance to see it, you know. 23 Q Okay. When you saw her in Boston, how was her 24 ability to communicate developing? 25 A Who? Teddy? 18 1 Q Yes. 2 A The baby? 3 Q Yes. 4 A Her ability to communicate with people? 5 Q Yes. 6 A Well, she's not talkative, she doesn't say that 7 much; but she can understand commands and everything, and 8 she communicates with eyes, with her eyes. 9 Q Would you say she's still developmentally delayed 10 in that respect? 11 A Well, she's behind, yes, I would say that. 12 Q Okay. And in developing her ability to 13 communicate, would the environment be of importance that 14 she's living in? 15 A Oh, yes, she has to be stimulated. 16 Q Okay. 17 A She has to be in an environment that understands 18 her needs and her ability to communicate, they're specific 19 and she needs to be stimulated the right way, if possible 20 all day long. She needs to receive the correct impulses 21 all the time. 22 Q Okay. And if a parent were able to give her that 23 personal attention, do you believe that that would be of 24 assistance to her? 25 A The attention that her daddy gives? 19 1 Q Or -- yes. 2 A Or her mom gives? 3 Q Yes. 4 A Or whoever gives her personal attention; is that 5 your question? 6 Q Yes. 7 A Yes, I think she's the kind of child who needs 8 interpersonal relationships. She's not just a child in a 9 group of other children, you know what I mean? 10 Q Yes. 11 A She needs and wants one basis intervention at the 12 moment. 13 Q Okay. 14 A Because she was much more withdrawn in the 15 beginning, and now she's developing into a sociable little 16 girl, you know. 17 Q Okay. 18 A So she still needs this interpersonal attention. 19 Q Is there anything else that you can add that you 20 would think would be of importance in understanding this 21 child and her development in the future? 22 A I don't think so. I think that they should 23 continue, what Susan said, they should continue the search 24 for the etiology. We excluded some of the entities, but 25 not all of them. Maybe if she goes to New York to a big 20 1 center they would come up with fresher ideas. 2 Q Okay. 3 A I don't think that we miss anything from the 4 intervention point of view, meaning that I don't think we 5 missed the diagnosis, that we could do something 6 differently, drastically different to change the situation. 7 Q Okay. 8 A But from the etiological point of view, we're not 9 clear what exactly is her disease. 10 Q Okay. Thank you. The other attorney may have 11 some questions now. 12 A Yes. No problem. Thank you. 13 14 EXAMINATION 15 BY MS. SANZ: 16 Q Dr. Skouteli, this is Cristina Sanz. Can you 17 hear me well? 18 A Very well. 19 Q Okay. When the family was visiting in Greece -- 20 A Uh-huh. 21 Q -- were you aware that the pediatrician here in 22 the United States, Dr. Williams, was also concerned about 23 some developmental delays? 24 A I don't, I don't remember that very well, because 25 the Greek pediatrician was the one who called me and asked 21 1 me to see this child. 2 Q So you're not aware Dr. Williams had seen her 3 prior to that? 4 A I don't remember this detail. You see, I 5 remember one day receiving a phone call from my Greek 6 colleague to see this child. Maybe the pediatrician was 7 concerned, too, but I'm not in a position to answer this 8 question correctly. 9 Q Okay. And when you diagnosed Teddy at that time, 10 you felt that she had psychomotor retardation? 11 A Yeah. 12 Q And one of the concerns you had was also for Rett 13 syndrome. You wanted to exclude that as a possibility? 14 A That was one of the possibilities. The other 15 one -- Rett syndrome; the other one was happy puppet 16 syndrome; some other chromosomal abnormalities were 17 excluded also. I suggested a CAT scan for cerebral 18 digenesis. Lots of things, you know, that crossed my mind. 19 Q Okay. And actually, eventually, in fact more 20 recently Teddy was seen by a Dr. McGinnis here in Portland, 21 Oregon? 22 A Yes. 23 Q And he, I'm sorry, she excluded, she determined 24 that Angleman's [phonetic] syndrome was not -- 25 A That was a good thing that they did that. 22 1 Q Okay. And I believe Mrs. Coutsoukis forwarded 2 the medical records to you to review? 3 A Uh-huh. 4 Q From Dr. McGinnis; is that correct? 5 A Yes, it is correct. I have the records. 6 Q Okay. 7 A Not in front of me right now, but I have them in 8 her files. 9 Q Yes. You talked about the kind of activities you 10 feel that Teddy would benefit from. 11 A Uh-huh. 12 Q Would those kinds of activities, could you give 13 me examples, what you mean by that? 14 A Well, I think she would benefit from a school 15 setting, to start with, like go in a special kindergarten 16 with physical, occupational, speech therapy, special 17 education, like two to three hours per day, in a specific 18 interventional setting; that's the first thing. 19 Q Yes. 20 A Secondly, I think she would benefit from physical 21 activities in general, like walking, climbing, cycling with 22 easy bicycles, any kind of physical thing. 23 Q Swimming? 24 A Yes. 25 Q How about interaction, or at least some 23 1 interaction with other children? 2 A Yes. Yes, of course. Not all day long, though, 3 because she needs interpersonal attention. 4 Q Yes, it has to be focused and part of a program? 5 A Yes. Yes. Of course she enjoys other children; 6 she's becoming sociable, I agree. 7 Q Okay. Thank you very much. 8 A Sure. 9 MS. CRAIN: I think we're finished, Dr. 10 Skouteli. And thank you for extending your day for us 11 so that we could take your deposition. 12 THE WITNESS: Okay. No problem. 13 MS. CRAIN: Thank you and good-bye. 14 THE WITNESS: Thank you. Bye-bye. 15 16 (The deposition was then concluded at 17 10:05 a.m.) 18 19 20 21 22 23 24 25 24 1 CERTIFICATE 2 3 STATE OF OREGON ) ) ss. 4 County of Jackson ) 5 6 I, Debra J. Dugan, a Registered Professional Reporter 7 and Certified Shorthand Reporter for Oregon, do hereby 8 certify that, pursuant to the stipulation of counsel for 9 the respective parties hereinbefore set forth, HELEN 10 SKOUTELI, M.D. telephonically appeared before me at the 11 time and place mentioned in the caption herein; that at 12 said time and place I reported in Stenotype all testimony 13 adduced and other oral proceedings had in the foregoing 14 manner; that thereafter my notes were reduced to 15 typewriting under my direction, and that the foregoing 16 transcript, pages 1 to 23, both inclusive, constitutes a 17 full, true, and accurate record of all such testimony 18 adduced and oral proceedings had, and of the whole thereof. 19 WITNESS MY HAND AND CSR STAMP at Medford, Oregon, this 20 6th day of December, 1996. 21 22 23 _____________________________ 24 Debra J. Dugan, RPR, CSR Certified Shorthand Reporter 25 CSR No. 90-0095