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O

Oligo
See: oligonucleotide

Oligogenic
A phenotypic trait produced by two or more genes working together.
See also: polygenic disorder

Oligonucleotide
A molecule usually composed of 25 or fewer nucleotides; used as a DNA synthesis primer.
See also: nucleotide

Oncogene
A gene, one or more forms of which is associated with cancer. Many oncogenes are involved, directly or indirectly, in controlling the rate of cell growth.

Open reading frame (ORF)
The sequence of DNA or RNA located between the start-code sequence (initiation codon) and the stop-code sequence (termination codon). A stretch of DNA that when translated into an amino acid sequence doesn�t contain an internal stop codon. An ORF can be evidence that a DNA sequence is part of a gene.

Operon
A set of genes transcribed under the control of an operator gene.

Overlapping clones
See: genomic library


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